You are your own company - "Me, Inc." Your ability to translate the facts of your life into a story will dramatically impact the opportunities you have.
If you've done the research, you're sitting on insights way more valuable than the average applicant
Go find some cool accounts, figure out who's got interesting Tweets, and follow them. Create a habit of a few minutes a few times a day keeping up on happenings in your spheres of interest.
You can't get a job interview because a resume will not get the hiring manager's attention in 6 seconds. No matter how nicely formatted.
Bottom line, it's in your hands. Get creative, put in some work, follow-up, and you will get better jobs faster than the typical approach.
People who are sharp enough to stop and think about the job hunt instead of just plodding along like the masses are often also people who can think too much.
Relax, it's not as stuffy as you think.
Send PROOF you can do THIS JOB by doing some of it ahead of time!
It's gonna take more work up front, but it will pay off, as each additional effort after will be easier and more effective.
Have you seen most resumes and cover letters? Not only are the uninteresting, they are utterly humorless and unfun.
The most important audience is you, and the most important story to learn to tell is your story.